As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.

The Easter Bunny is tired of being second-best to Christmas, so he hires Lobo aka The Main Man to take out Santa Claus in order for him to rule over the Holidays. But nothing goes as planned when The Main Man is involved.