The O'Donnells are a typical, everyday family -- Tad (George Hernandez) is a sensible working man, his wife (Fannie Midgely) is a good mother and their daughter Kathleen (Constance Binney) is pretty and innocent to the point of naiveté. Kathleen works in a factory and its owner, Donald Holiday (Warner Baxter), has taken a shine to her. But instead she falls for slick cab driver Harry Stanton (George Webb), who insists, "Honest, kid, you're the only girl I ever loved." Kathleen falls for this, and when her perceptive father makes clear he doesn't approve of Stanton, she moves out on her own.

When, on a prank, shimmy dancer Marcia Meadows visits bookworm Horace Tarbox in his Yale dormitory, Horace falls madly in love and follows her to New York where he and Marcia marry. Denounced by his wealthy father, Horace attempts to support Marcia through his writing, but all his manuscripts are rejected, and he is fired from every job.

A feud exists between two outback families, the Blakes and the Ridgeways, caused by Sam Ridgeway having married a woman Jim Blake was in love with. The feud goes on for over thirty years.