When Rengganis’ love for a fellow student at her martial arts school is spurned, she steals his magical power and turns into a Siluman Laba-Laba (Spider Demon). She then attacks and murders innocent people until her teacher sends his prized pupil Senjoyo after her armed with magic.

Immediate sequel to Sengatan Laba-laba Merah ("Sting of the Red Spider"), released earlier the same year. Evil spider woman Rengganis aka Laba-laba Merah (Red Spider) is baaaack! Only heavily injured (not killed... suckers!) from the climactic fight in Round 1, Rengganis runs away and meets up with her former karate teacher's arch nemesis. The two cause all kinds of problems and kill all kinds of people but Rengganis is also looking for a cure as turning into an ugly spider monster all the time is growing rather tiresome for her.