Hard-drinking novelist Zach Hutton spirals out of control after his wife and mistress both leave him. Alone and crippled by a bad case of writer's block, Zach slips in and out of casual relationships and one-night stands, while his drinking becomes more and more severe. With the help of a bartender and his therapist, Zach confronts his demons — women and alcohol.

Edward is busy trying to unlock the secrets of reading and recording people's thoughts. He is very involved with his work leaving little room for girlfriend Britt. Longstreet comes along and offers Edward a place to do his research and have unlimited funding. There are, however, ulterior motives as Edward is also somehow unlocking the secrets of eternal life.