Thomas, a blasé young man, spends his nights in clubs and his days in bed. Until his father, Dr. Reinhard, fed up with his son’s escapades, cuts him off completely and forces him to take care of one of his young patients. Mar- cus, 12, was born with a serious congenital disorder. He lives with his mother in the poor suburbs of Paris and spends his days either at the hospital or in a center for sick children. This encounter will disrupt their lives and change them both, profoundly and forever.

Alexis Pasquier, a young French teacher, begins his first day of classes at the Nancy prison. There he meets Léa, a young woman with whom he falls madly in love. Two worlds open up to him: true love and the prison environment. He will never be the same anymore.

Le Dernier Caravanserail (Odyssées) is a series of stories, scraps of destinies, bits of the lives of men and women – of those "refugees", "illegals" and "migrants" who term themselves, with greater dignity, "travellers". This is a veritable ocean of time-battered odysseys, sometimes heroic, sometimes commonplace, and always dramatic. Initially a work for the theatre, Le Dernier Caravanserail (Odyssées) is now a film. A whole new artistic adventure using the cinema to bring even greater depth to the virtually inexhaustible original material, and intended above all to keep the promise made to those whose stories we are telling: to give them a hearing.