A family is torn when their teenage daughter (Reese Witherspoon) is diagnosed with leukemia and their medically-unstable son is the best bet for a bone marrow transplant

Sixteen-year-old Cassie Robbins is a spirited teenage girl, who loves her father Richard and stepmother Mel and dotes on her six-year-old half-brother Willy. But her carefree, happy life is forever changed when she is diagnosed with leukeamia and her only hope of a cure lies in a bone-marrow transplant. However, when Willy proves to be a match, Mel is not-so-willing to allow her young son to undergo surgery as he nearly died the last time he was operated on after reacting badly to the anaesthetic. Mel and Richard now have to decide if it right to risk the life of one of their children to save the life of the other child. And of Willy's own rights in deciding if he should help the sister he hero-worships...?

Just retired from the Drug Enforcement Agency, John Hatcher returns to his hometown and quickly discovers that drugs have infiltrated his old neighborhood. Determined to drive the dealers out, Hatcher crosses paths with a ferocious Jamaican drug lord who vows that Hatcher and his family are now marked for death.

After a one night stand with Alex, Isabel realizes that she is pregnant and they decide to get married. However, along with the marriage comes compromise of one's own cultural traditions.

This women in prison drama tells us a story about the mother of three children, who was falsely accused for a crime she did not commit (drug dealing), arrested and locked up behind bars.