Alice Tate, mother of two, with a marriage of 16 years, finds herself falling for a handsome sax player, Joe. Stricken with a backache, she consults herbalist Dr. Yang, who realizes that her problems are not related to her back, but in her mind and heart. Dr. Yang's magical herbs give Alice wondrous powers, taking her out of her well-established rut.

Nerdy high schooler Arnie Cunningham falls for Christine, a rusty 1958 Plymouth Fury, and becomes obsessed with restoring the classic automobile to her former glory. As the car changes, so does Arnie, whose newfound confidence turns to arrogance behind the wheel of his exotic beauty. Arnie's girlfriend Leigh and best friend Dennis reach out to him, only to be met by a Fury like no other.

The younger brother of an assassinated US President is led down a rabbit hole of conspiracies and dead ends after learning of a man claiming to be the real shooter.

Some unknown source has interrupted all television transmissions around the world. In place of the regular broadcasts, a lineup of extremely tasteless programs and commercials have been substituted. Included in the mix are such show as The Shitheads, The Charles Whitman Invitational, and commercials for a number of improbable products.

A hired killer hunts down a schoolteacher to get something she has. She doesn't know what it is, but he's already killed twice to get it.

In 1979, a delivery truck makes its way up a lonely southern California highway in a storm, bound for the San Diego Zoo with a deadly tropical rattlesnake as cargo. When the truck suffers a blowout, the driver loses control and hits a tree, shattering the snake's aquarium in the back and the window separating the snake from the driver. The snake slithers into the front of the truck, kills the driver with its bite and then moves off into the forest. Flash forward to 1999. The small southern California town of San Vicente has grown from 6,000 to 30,000, and the rattler, which escaped nearby years ago, has bred. There are now 25,000 of these hybrid rattlesnakes, and they are slowly making their way downhill into the town, attracted by the movement of the blasting as the town paves its way toward progress. Progress, in this case, brings terror, in this tale originally penned by John Carpenter.

A small town becomes gripped by an ethical debate when the community discovers a moody, egotistical scientist is experimenting with DNA and the creation of new life.

Middle-aged widow Beatrice Hunsdorfer and her daughters Ruth and Matilda are struggling to survive in a society they barely understand. Beatrice dreams of opening an elegant tea room but does not have the wherewithal to achieve her lofty goal. Epileptic Ruth is a rebellious adolescent, while shy but highly intelligent and idealistic Matilda seeks solace in her pets and school projects, including one designed to show how small amounts of radium affect marigolds.

A man falls in love with a married co-worker and wants her to divorce her husband, but she refuses because she has a ten-year-old son.

Dennis Weaver is a Joseph Wambaugh-type novelist cop and Pat Hingle is his hard-nosed superior who wants him to stick to police work or get off the force in this pilot to the short-lived series.