While Louie is on vacation, the boys turn The Sweet Shop into an escort service, and soon find a group of beautiful girls as their first clients.

The gang is sent to the Wilton Reform School after they are unjustly convicted of stealing a truck. Bill Collins, brother of co-leader Danny, becomes involved in a killing and, while also innocent, is convicted and sentenced to death. Through a series of events, Muggs, Glimpy, Danny and the rest of the gang, learn that Knobby, a henchman of Luke Manning, knows something about the murder.

Slip and Sach take the rap for a robbery they did not commit in order to uncover the real robbers, whom they suspect are led by a convict who gives orders to his gang outside via a short-wave radio stashed somewhere in the prison.

A group of delinquents on their way to summer camp get stuck in a haunted house.

The East Side Kids discover that one of their own, Danny, is torn between staying in school and becoming a boxer, and is getting mixed up with gangsters.

The boys get mixed up with a race horse & crooked gamblers

The Dead End Kids join the war effort in this feature-length version of the Universal serial Junior G-Men of the Air. The fiendish Black Dragon Society, led by the sinister Baron (perennial B-movie villain Lionel Atwill) plots to pave the way for an Axis invasion of the U.S.A. by destroying America's defenses. When their plans are discovered by the Dead End Kids, the gang is too suspicious of "the coppers" to ask for help. The FBI send in their Junior G-Men to stop the spies, but when one of the Dead Enders is kidnapped, the two groups must work together to smash the Black Dragons once and for all!

Slip and Sach's boss, David J. Thurston, has allegedly committed suicide. Slip finds a book of matches with the name of a local nightclub on his boss' desk and finds out from Gabe that a gambling casino is being run out of it. Slip comes to the conclusion that the club had something to do with his boss' death and sets out to find his murderer. The boys get jobs at the club and Louie poses as a rich cattlemen as they gather the information to convict the murderers.

One of the Bowery Boys gains superhuman strength, and he cashes in by becoming a pro wrestler.

The Bowery Boys--Slip, Sach, Bobby, Whitey & Chuck--start their own exterminating service, and get a job which takes them to a spooky old abandoned mansion in the middle of the night. Meeting up with pal Gabe and his new French bride, the boys are tormented by mad scientists who try to convince them the place is haunted and then kidnap Sach in order to place his brain inside a gorilla.