Mrs. Booker on 8th Avenue follows Florence Booker who feels increasingly isolated in her marriage in New York. A shared cigarette with an alluring line cook sparks an affair that causes the different layers of Florence's life to unravel.

Three people gather for an "uncoupling celebration" arranged by a struggling writer and his mistress. When the power goes out during a thunderstorm, the deepest truths are revealed, changing each person's life forever.

Would you fall in love with a homeless person? Six years after Occupy Wall Street, Jehan is 42 years old and homeless on the streets of New York City. As she works to save money, get an apartment and return to a "normal" life, she decides that she would also like to get married. Would someone willing to put a dollar in her begging bag also be willing to fall in love with her? Can she find true love with a "normal" person?

Anna and Joel Kemp's joy over their expected baby is shattered when Anna's cancer returns. They face an agonizing decision: pursue treatment now or delay it, with either the mother's or unborn child's life at stake.