Ignacio, a disrespected cook at a Mexican monastery, can barely afford to feed the orphans who live there. Inspired by a local wrestling hero, he decides to moonlight as the not-so-famous Luchador "Nacho Libre" to earn money for the monastery -- not to mention the admiration of beautiful nun Sister Encarnación.

Bruce Nolan toils as a "human interest" television reporter in Buffalo, NY, but despite his high ratings and the love of his beautiful girlfriend, Bruce remains unfulfilled. At the end of the worst day in his life, he angrily ridicules God — and the Almighty responds, endowing Bruce with all of His divine powers.