Born to Be Wild observes various orphaned jungle animals and their day-to-day behavioural interactions with the individuals who rescue them and raise them to adulthood. The film unfurls in two separate geographic spheres. Half of it takes place in the rain forests of Borneo, where celebrated primatologist Dr. Birute Galdikas assists baby orangutans; the other half takes place on the arid savannahs of Kenya, where zoologist Dame Daphne Sheldrick works with baby elephant calves.

This unique historical film follows the struggle in Kenya's Tsavo National Park against bow and arrow poachers who kill elephants and rhino, and the story of hand-rearing elephant and rhino orphans whose mothers were killed by poachers.

Footage of the investigation documentary telling about the extermination of African elephants lasted almost three years. The film crew traveled throughout 30 countries to make a route of ivory smuggling and to find out the true culprit of these crimes against elephants.