Finally released from prison, Elwood Blues is once again enlisted by Sister Mary Stigmata in her latest crusade to raise funds for a children's hospital. Hitting the road to re-unite the band and win the big prize at the New Orleans Battle of the Bands, Elwood is pursued cross-country by the cops.

Martial-artist Ray should focus more on his pregnant girlfriend, Tina. However, many others are in the picture, including (but not limited to): Tina's ex-boyfriend; Ray's sexually-discriminating boss-lady; and two homies.

Ten years after his original massacre, the invalid Michael Myers awakens on Halloween Eve and returns to Haddonfield to kill his seven-year-old niece.