A team of young aspiring filmmakers are searching for the ideal actress for a horror film. The candidates are forced to endure long torture scenes, which they cannot stop once begun, including strange incisions in different parts of the body with sharp instruments of various sizes, the use of cigarettes and blowtorches to burn the skin, the crushing of the toes at the point of a hammer, and other twisted things that leaving the girls as bleeding remains. This is alternated with direct explanations to the camera by the director, the producer, and the cameraman who explain their crazy criteria about art and the aesthetic-dramatic sense of the scenes.

In 1995, several cargo containers are discovered high in the Bolivian Andes. Inside are potentially toxic chemicals, and local policeman Mariscal soon becomes charged with the task of smuggling the containers into neighboring Chile. He recommissions an old train to haul the toxic waste out of Bolivia, but encounters one mishap after another, beginning with the local townspeople who know what's inside, halting the train's path.