Scientists using nano technology to shrink objects to microscopic size use their science on a deadly shark, which is injected into a person's bloodstream in an attempt to cure a rare blood disorder. When the shark begins to do more harm than good, a team of adventurers enter the bloodstream in a shrunken submarine in an attempt to kill or be killed by the smallest great white of them all!

Something terrifying has returned to the tiny village of Salem’s Bluff. It’s a week before Thanksgiving, but this time, it’s the humans who are being carved up. Vicki Stanton, a professor of New England folklore, believes the culprit is none other than the dreaded "Gobblefoot"—a mythical creature, half turkey, half Bigfoot, that stalked these very forests 200 years ago. Will the residents of Salem’s Bluff survive to enjoy their pumpkin pie, or will they all fall prey to the monstrous Gobblefoot?