Jessie deals with a bad breakup, by purchasing a sheet of acid to share with his friends back home in Missouri. He hopes this will erase the bad memory of his college girlfriend, delivering the heartbreaking news to him, during sex. Departing New Orleans, Jessie detours onto Route 61, seeking a change of routine from the monotony of the Interstate. Unexpectedly, his engine fails at a forgotten trailer park in Cleveland, Mississippi. Fearful he's about to be harmed by bikers, Jessie exchanges hits of L.S.D. for safe passage home. During the ebb and flow of the day, Jessie experiences the extraordinary in the pedestrian, whilst resurrecting the lives of many. Inspired by a true misadventure.

Plucky and innocent Laci Cox is hired to teach a rowdy and experienced group of hormonal high schoolers about sex. The only problems is... she's a virgin! Laci must lose her virginity before she loses her job.

When New Orleans Police Detective Danny Fisher stops a brilliant thief from getting away with a multimillion-dollar heist, the thief's girlfriend is accidentally killed. After escaping from prison, the criminal mastermind enacts his revenge, taunting Danny with 12 rounds of near-impossible puzzles and tasks that he must somehow complete to save the life of the woman he loves.

Janet and Michael are a young couple trying to balance their life and love with one another. When challenges come up that threaten that bond they have to figure out how to keep their love strong or let it go. They have to figure out what love is.