A closeted young woman brings her girlfriend home for Thanksgiving, only to have her coming-out efforts thwarted by the unexpected arrival of her male roommate.

Investigative reporter George moves to New York, but needs a roommate. Knowing no one else in the city except her childhood best friend Trish, George agrees to move in with Trish’s city bestie, Avery, an aspiring actress and full-time mess. Due to a clash of personality and a series of mishaps, the two women quickly end up at each other’s throats – and competing for Trish’s friendship. Until one day when Trish mysteriously vanishes. The women are then reluctantly forced to team up to track down their friend, only to discover that Trish’s disappearance is just the first of many secrets.