In 1920s Dutch East Indies, Giandra, a young doctor from STOVIA, reads about Layla—a girl shackled in a remote village as a "cure" for mental illness. Disturbed, he travels to Karuhun, where tradition and mysticism prevail over science. Guided by journalist Rikke, who warns him with three words—Culture. Mysticism. Superstition.—Giandra must confront a clash between modern medicine and ancestral belief.

Three years after climbing Mount Madyopuro, the five friends' friendship has grown stronger. When they reunite for Andrew's daughter's birthday, they witness the family threatened with becoming a sacrifice for a black magic ritual! They set off to accompany Andrew to Mount Klawih. However, Juna has disappeared into the realm of demons!