To keep their struggling used-car dealership from closing, salesmen Sid and Bob agree to let a vintage 1963 Pontiac LeMans sit on their lot for two days in return for $250,000. Warned that the vehicle has been associated with many deaths already, Sid and Bob are soon pursued by hitman Mr. Reich and FBI Agent Jared, among others. As violence surrounds them, Sid talks his partner into stealing the car for a $500,000 ransom.

Narcotics Sergeant Nick Tellis, on leave after a trauma, is called back to investigate the murder of fellow undercover operative Michael Calvess, joined by the victim's unpredictable and brutal ex-partner, Henry Oak. Working together in the back alleys of Detroit, Tellis and Oak delve into a dark investigation that leads them to uncover shocking secrets and question the corruption and morality within the department, encountering unorthodox methods and a brutal truth about Calvess's death.

A supposed treasure map leads a group of unsuspecting townspeople to the lair of a vampire-like creature known as El Chupacabras.