When his home of New Eden is destroyed by a revitalized Brotherhood and its new Vamp leader, Martin finds himself alone in the badlands of America with only the distant memory of his mentor and legendary vampire hunter, Mister, to guide him.

The Lunar Base Ark explores ore and unexpectedly is hit by a meteor shower and has severe damages. Colonel Gerard Brauchman sends the crewwoman Ava Cameron to repair a wing that is full of CO2. Dr. Lance Krauss warns that the gas may cause paranoia and hallucinations. Ava brings a sample of the meteor for analysis and Dr. Krauss finds that there are spores attached to the meteor. Ava accidentally cuts her finger in a sample but she hides the cut from the doctor. Soon Ava gets pregnant and delivers an alien offspring. However, neither Col. Brauchman nor Dr. Kraus believes in her words and they believe that Ava is delusional. The offspring bites the crewman Bruce Johns and the crew discovers that Bruce has been cloned by the alien. Soon they find how dangerous the clone is.

Forensics students arriving on an isolated island "body farm" get to try out their CSI skills on a bunch of corpses under the watchful eye of their grumpy professor. The island used to house a state penitentiary, where the authorities were experimenting on death row inmates, and now the bodies won't stay still.