After a heavy night out with the girls, Isabel, and attractive young professional woman catches an illegal mini-cab home. Things take a turn for the worse when the cabbie pulls her into an ally and violently forces himself onto her, taking her life. From high above on the rooftop, an ancient female Vampire notices. Taken in by Isabel's beauty and innocence, she dispatches the Cabbie and feeds Isabel a drop of her immortal blood. Isabel awakes with 48 hours to decide whether to embrace immortality, or kill herself before she becomes undead.

Meet Peltzer Arbuckle, a bullied office employee, humiliated by his megalomaniac boss, teasing colleagues and cheating partner. Stuck in his mundane, nightmarish reality, once news about an embarrassing sexual accident circulates the workplace, Peltzer decides to put up with his misery no more, and conjures up his childhood imaginary friend Ronnie who manipulates him to exact gruesome revenge on his tormenting co-workers. As the body count rises, Peltzer must either run away from his past or take control of his future, battling between sanity and madness in a twisted tale of infidelity, revenge and snapped banjo strings.

A dark figure appears in the night, bringing with him a virus that turns people into monsters. Hoping to gather stories to take back with him to the other side, he meets his opposite, a light figure prepared to do battle with the dark man in order to save the human race...