Lupin steals an extraordinary gem from a Mediterranean party, only to be interrupted by Pycal, the trickster "magician" who had apparently died fighting Lupin early in his career. Pycal, now armed with real magical abilities, is determined to take revenge.

Secretly operating his cruiser as a casino at sea isn’t enough for mafia don Lukino Marcano. He’s also looking for the gold-laden boat wreckage worth the budget of a small country! Lupin sniffs out the plan to recover this long-lost treasure and brings along his partners Jigen, Goemon, and Fujiko for the ride to crash Lukino’s party.

The stickup that started it all! Lupin III and Fujiko are both after an ancient artifact Jigen is supposed to protect, while Goemon happens to be searching for his clan’s lost treasure nearby. Of course, Inspector Zenigata isn’t far behind. This is the story of our heroes’ very first meeting!

Fujiko and Lupin are kidnapped by Malkovich, a notorious criminal escaped from Alcatraz who forces Lupin to steal the "Bull's Eye," a precious stone.

In Karakura Town, unidentifiable spirits begin appearing en mases. While attempting to deal with these strange souls, Ichigo Kurosaki and Rukia Kuchiki meet Senna, a mysterious shinigami who wipes out most of them. Senna refuses to answer any questions, so Ichigo is forced to follow her while Rukia tries to find out what's going on.

The year is 21XX. Reploids are commonplace now, after Dr. Cain rediscovered Dr. Light's old lab and based several designs off of Dr. Light's original, called "Mega Man X". X, meanwhile, has joined the Maverick Hunters, and works with unit leader Zero under the command of Commander Sigma. It is their job to terminate reploids who have become violent.

The story focuses on the exploits of rivals Reinhard von Lohengramm and Yang Wen-li, as they rise to power and fame in the Galactic Empire and the Free Planets Alliance, respectively.