When Donna’s mother Eve dies, her sister inherits everything of value; all Donna gets is a list of addresses and mementos from her mother’s life, to be delivered to the significant people of her past. Her mother’s dying wish sends Donna on a road trip from Texas to Arizona to make peace, uncover secrets, and find understanding in the life she's been dealt.

Dr Dennis Slamon, an American oncologist, discovers a treatment that could possibly cure breast cancer without radiation or chemotherapy. He tries to look for ways to fund the medication.