Tom Hanks is the host of this show with a comic approach to raise awareness concerning the environment.

A psychotic man opens fire in a diner, murdering numerous people before killing himself. The survivors struggle in different ways following this horrendous event: a doctor doubts his own instincts and elects to use an experimental medical procedure on his wife, while a gambler believes he's on a lucky streak. A waitress begins engaging in promiscuous sex, and a young girl whose father is among the dead gains unexpected fame.

All her life, Cathryn Bailey has seen herself as extremely lucky. She has a loving wife (Helen Martin), two beautiful though sometimes challenging young sons, and a mother (Isobel Bailey) who has been not only present but a key participant in every major moment of Cate's life. No matter what, Isobel has always found a way to lift her daughter up and instill a sense of indomitable strength in her family. When Isobel is diagnosed with Alzheimer's though, her ability to fulfill her role as matriarch and caregiver begins to unravel, and Cate suddenly finds herself struggling to care for everyone. Helen, the boys, Cate's brothers...everyone tries to find a way to help Cate with Isobel but, in the end, no one knows how to let this magnificent woman go.