The world has woken up surprised by a massive catastrophe, the disappearance of millions of people who are apparently homosexual. Ale, a girl who was adopted by a same-sex family, is in danger, as the country's government is taking preventive measures in light of the event, and intends to return all the children who were adopted by these families to the orphanage where they came from.

Elisa is an old-fashioned girl who receives the visit of her future self, who advises her to take the risk and invite Carlos, his best friend, on a date. She has always been attracted to him.

Saltillo, a small dusty town south of the Mexican border, caught in a war of greed and corruption. A man named Bishop returns home after his parents are executed at the hands of a ruthless drug lord El Chilango. He swears to avenge the deaths of his loved ones and take down every person involved at the cost of losing himself and his new love Lucia, the wife of his new arch rival El Chilango.