A young man with Asperger's Syndrome falls in love with a sheltered young woman who suffers from Mitral Valve Stenosis, a congenital heart condition. Will his condition cause her demise or will his love be the greatest gift she can ever receive?

The movie follows a group of teenagers that are terrorized by an evil spirit. The film revolves around the traditional Filipino belief that one should never go home directly after visiting a wake since it risks bringing evil spirits or the deceased to one's home.

When Section Zamora contracts a mysterious virus during a field trip, they are quarantined by the military in an abandoned facility. Students Ada, RJ, Princess, and Migs fight for their survival as they deal with the dangers of the infectious virus and politics among untrustworthy classmates.

A spoiled rich boy sent to province who meets a hardworking poor girl, and through constant clashes and shared struggles, they grow as individuals and eventually fall in love despite their different worlds.