51 avant Jésus Christ. A la mort de leur père, Cléopâtre et son jeune frère Ptolémée héritent d'un immense empire : la terre fabuleuse des pharaons d'Égypte. Ecartée du pouvoir par son frère qui va jusqu'à tenter de l'assassiner pour régner seul, Cléopâtre est déterminée à recouvrer ce trône qui lui revient de droit.

Lucretia is a killer for hire. Specialised in poisoning and passionate about opera, she'll have to fulfill a difficult contract in the heart of the Swiss alps. Posing as a singer, Lucretia will have to appear on the scene of the higly exclusive Festival d'Ermeux and try to kill one of her partners: British bariton Alexander Child. Having recently acquired a Scottish distillery, he remains the only obstacle to a strategic pipeline project with considerable economic stakes; having recently won a tough legal battle against British Oil, their last resort is to eliminate him. Complicating everything is Rico, sent by the French contra-espionage, who tries to infiltrate the orchestra and stop the plot against Alexander Child.

Pete and Debbie are both about to turn 40, their kids hate each other, both of their businesses are failing, they're on the verge of losing their house, and their relationship is threatening to fall apart.