A couple stay in a dingy motel in Maine to try and escape their hectic lives, but are haunted by spirits of previously murdered guests.

Homicidal maniac Marc is constantly driven my demons buried deep within his soul while his estranged sister Wendy is Marc's polar opposite and lives life fast and hard without a second's thought to the consequences. Their separate paths will eventually cross, but will it be on the road to salvation or the highway to hell?

A vampiric doctoral student tries to follow the philosophy of a nocturnal comrade and control her thirst for blood.