After a group of boy scouts are mysteriously killed by a wolf-like creature on Cadaverous Island, Walter Romero, whose best friend was among the killed, sets out to find exactly what happened. In order to reach the island, Walter teams up with Johnny Mason, neighborhood stoner, to smoke up Ashley Valinski, neighborhood hottie, and get her to take them out on her father's boat. But soon after arriving on Cadaverous Island, a horde of zombies steals their boat, leaving them stranded, and the three are forced to team up with two cops, the mayor, and a team of botanists to either kill the monsters... or be killed themselves..... DUN-DUN-DUN!!!

A young woman named Wren finds herself lost in the desert after she and her two druggy friends flip their jeep in a remote part of Mexico. In their attempt to reach the nearest town by way of the desert, a symbolic journey unfolds as Wren begins to hallucinate, envisioning Death is stalking her in various forms: as a demon and an enchantress.