Mr. Dithers is trying to encourage a businessman to build a war-time manufacturing plant on land he owns while Dagwood tries to prevent the businessman from learning his daughter is involved in a local theatre production.

Daisy, the Bumstead's mischievous mutt, makes the family a little extra cash when she wins a contest to become a model for the Navy. From there she becomes the favorite calendar gal. All the attention to the dog, makes Dagwood feel that his position as master of the house is jeopardized. Meanwhile all the attention catches the greedy eyes of gangsters who try and abduct Daisy!

Blondie organizes Housewives of America to perform home-front wartime duties, including guarding the local dam... Blondie for Victory was twelfth in Columbia's series of comedy films based on Chic Young's popular comic strip Blondie. Anxious to do her bit for the war effort, Blondie joins the Housewives of America, a home defense league. Husband Dagwood soon finds that Blondie is neglecting her responsibilities at home in favor of her war work; also disgruntled are Dagwood's chauvinistic boss Mr. Dithers and a newlywed husband whose wife is never home thanks to the defense league.

Cookie is born, producing unmitigated joy in the Bumstead household. Adding to the chaos a new baby always creates is the appearance of Hans Conried as a cynical author who becomes caught up in the Bumstead lifestyle.

Mr. Dithers invites the Bumsteads on a South American cruise. Somehow Dagwood winds up as the female drummer in the ship's band, while Penny Singleton gets to show off her Broadway background in some lively musical numbers.

Older but no wiser, Blondie and Dagwood Bumstead enter a songwriting contest. It's all part of a plan to cover charity checks that they've signed separately but can't cover. Along the way, Blondie's blood boils when Dagwood gets innocently mixed up with beautiful music teacher Rita Rogers.

Not only must Blondie put on a brave face when her husband Dagwood is fired for the umpteenth time by Mr. Dithers, but she must also tolerate the attention paid to Dagwood by pretty WAC Mary Jane McDermott. A whiz in business matters, Mary Jane sets up Dag in his own business, which replenishes the Bumstead coffers but which drives Blondie into a jealous frenzy.

Blondie decides she wants to be a star and nearly turns her household upside down in this entry in the long-running domestic comedy series. Dagwood has mixed emotions about his wife's theatrical aspirations and eventually he decides to get her to quit. As usual - disaster ensues.

BBlondie opens a bakery in her home to help fill the family cookie jar. Her tasty cookies become so popular that a cookie magnate makes her an offer that is difficult to refuse. Unfortunately, this creates all kinds of problems for the Bumsteads.

Dagwood prepares for a long-delayed vacation with the family. His boss Mr. Radcliffe has promised the Bumsteads that there'll be no more postponements for their holiday. But when something comes up that requires Dagwood's presence, Radcliffe hires a couple of thugs to steal Blondie and Dagwood's luggage so that they'll have to stay in town. And that's only the beginning of the frantic fun.