Isabelle and her niece Nina open a "fasting and detox" cure in the heart of Provence, with the help of Baptiste, a yogi and handyman, Jessica, a tantric masseuse, and Maxime, a seductive equine therapist. Among the first curists, four overweight teenagers sent by the town hall; Marion and Lio, her skinny sister who imposes the cure on her "for her own good"; and their friend Émilie who, having shed her extra kilos, discovers as soon as she arrives that her beloved husband is swooning in the arms of a man... who is clearly overweight!

Angélique is a nursery school teacher. She loves the children: other people's, of course, and those of her partner Damien, who is going through a divorce. It is then that she realizes that she has contracted a very rare allergy... to children!

An aging gangster (Jean-Pierre Mocky) escapes from prison and is taken in by a very beautiful blonde who asks him to kill her uncle (Richard Bohringer) because he guards her money but prevents her from using it. She asks the gangster to kill him and that way she won't turn the gangster in - she knows he's escaped. The gangster prepares to kill the uncle, except that he realizes he's a very good guy. He becomes friends with the uncle. He won't kill him and will simulate the murder.

Three women from Brest. Léanne, the cop, a hothead whose ambition knows no bounds. Élodie, the forensic pathologist, a settled family woman. Vanessa, the psycho-criminologist, a fiercely independent and outspoken woman. Three childhood friends reunited since Léanne's recent return to Brittany following the death of her husband during an operation. Together, and despite their radically different personalities, they will hunt down the region's criminals while juggling their lives as women, trying their best to balance their work, family life, love, and friendships…