Nate Shepherd, late 40's, and Jenny Sparks, early 30's, meet in a fancy New York eatery. Complete strangers who have had a rotten day, waiting for their better halves, they reveal to one another that they are going to meet new people tonight. They quickly realize they are waiting for each other. When Nate loses his girlfriend (after getting fired from his cushy job at an ad agency) and Jenny loses her boyfriend to a drug overdose, Nate's girlfriend suggests that they should move in together as friends to split the rent and ease each others pain. As their friendship grows into something more, their relationship becomes a loving but complicated experience.

When Lisa’s father is killed in a hit and run, we discover that he has a secret daughter from his first marriage. Her name is Marie and she is a convicted murderer, out on early release from prison, and driven by a single purpose–revenge. Living under a secret identity as Bethany, Marie has connived her way to living and working close to Lisa, lurking and planning her revenge as payment for the life she feels cheated out of–a life she feels their father unfairly gave to Lisa. Marie has set a deadly trap for Lisa to take back what she is owed, leaving Lisa, her mother and their friends to fight for their lives against the murderous sister she never knew.