Best friends Emily and Lesley go on a road trip to the desert. When Emily decides to get off the highway and take a "short cut," they become the target of a relentless and psychotic trucker who forces them to play a deadly game of cat and mouse.

A pragmatic PhD candidate must let go of her logic when she finds a list of items to give away written by the late mother she never knew. With the encouragement of her enthusiastic new mentor, she attempts to return everything on the list and begins to encounter unexplainable coincidences that lead her to understand the world’s smallest marvels have the greatest meaning.