In 71 BC in Rome, utter disorder reigns in the form of political corruption and bribery involving the senator Cynic (Leslie Nielsen). The situation is claimed to be similar to the “Tangentopoli” situation in Italy in the 1990s: one of the politicians involved was Bettino Craxi.

Detectives Marcus Burnett and Mike Lowrey of the Miami Narcotics Task Force are tasked with stopping the flow of the drug Ecstasy into Miami. They track the drugs to the whacked-out Cuban drug lord Johnny Tapia, who is also involved in a bloody war with Russian and Haitian mobsters. If that isn't bad enough, there's tension between the two detectives when Marcus discovers that playboy Mike is secretly romancing Marcus’ sister, Syd.

A group of Italian tourists on a Caribbean holiday finds itself stranded on a deserted island after a plane crash.