Two rival juice companies, Eco-Elixir and Jock Juice, accidentally unleash an experimental formula of energy drink on an unsuspecting group of concert- goers. This formula turns whoever is unfortunate enough to drink it into flesh-eating crazies!

After accidentally murdering her boyfriend, Debbie Dicky moves to a new town and meets three girls who invite her to a sleepover. The very same night there is a breakout at the local insane asylum where forty serial killers escape and head over to crash the party. However, the girls at the slumber party might not be as helpless as the killers think.