Not only is Jessica Spencer the most popular girl in school -- she is also the meanest. But things change for the attractive teen when a freak accident involving a cursed pair of earrings and a chance encounter at a gas station causes her to switch bodies with Clive, a sleazy crook. Jessica, in the form of the repulsive Clive, struggles to adjust to this radical alteration and sets out to get her own body back before the upcoming prom.

When loser Marvin Mange is involved in a horrible car accident, he's brought back to life by a deranged scientist as half man and half animal. His newfound powers are awesome -- but their adverse side effects could take over his life. Now, Marvin must fight to control his crazy primal urges around his new squeeze, Rianna, and his rival, Sgt. Sisk, who both think he's one cool cat.