An art professor is informed that the husband she thought died ten years before has just been murdered. So she starts to research her husband's secret life in search of the reason he disappeared and who might have killed him.

Duets is a road-trip comedy which revolves around the little known world of karaoke and the whimsical characters who inhabit it. All roads lead to Omaha, site of a national karaoke competition where this motley group of singers and stars come together for a blow-out sing-off.