Following the tragic death of her teenage son, Manuela travels from Madrid to Barcelona in an attempt to contact the long-estranged father the boy never knew. She reunites with an old friend, an outspoken transgender sex worker, and befriends a troubled actress and a pregnant, HIV-positive nun.

In Madrid, Azu's husband Filipe is smug and boorish, but it's his money she slips to family members constantly in need of cash and that she uses to buy gifts for her lover, Pablo. Things start to fall apart when Pablo wants to leave her and when Filipe wants to evict Azu's cousin from a butcher shop he rents. Azu hatches a plan that relies on her sister, her cousin the butcher, and his mentally-challenged delivery man. When things start to go wrong, can Azu make them right?

After more than 300 years in hiding, Dracula's brides, Luna, Adriana and his new apprentice Katya, must team up once again to stop the most diabolical threat from their past, his sister Mina.