A stranger stumbles into the desert town of Absolution with no memory of his past and a futuristic shackle around his wrist. With the help of mysterious beauty Ella and the iron-fisted Colonel Dolarhyde, he finds himself leading an unlikely posse of cowboys, outlaws, and Apache warriors against a common enemy from beyond this world in an epic showdown for survival.

Bruce Banner, a genetics researcher with a tragic past, suffers massive radiation exposure in his laboratory that causes him to transform into a raging green monster when he gets angry.