A young girl is raised in a dysfunctional family constantly on the run from the FBI. Living in poverty, she comes of age guided by her drunkard, ingenious father who distracts her with magical stories to keep her mind off the family's dire state, and her selfish, nonconformist mother who has no intention of raising a family, along with her younger brother and sister, and her other older sister. Together, they fend for each other as they mature in an unorthodox journey that is their family life.

The ghost of "patient zero", who allegedly first brought AIDS to North America - materialises and tries to contact old friends. Meanwhile, the Victorian explorer Sir Richard Burton, who drank from the Fountain of Youth and now works as Chief Taxidermist at the Toronto Natural history Museum, is trying to organise an exhibition about the disease for the museum's "Hall of Contagion".

Scatterbrained Polly gets a job as a secretary in Gabrielle's art gallery. Polly aspires to be a professional photographer, and idolizes Gabrielle for her artistic ability. When Gabrielle rekindles an old romantic relationship with the younger painter Mary, Polly becomes jealous, and discovers Gabrielle isn’t exactly who she claims to be.

The murder of a museum curator places art dealer Jack Saunders under suspicion for selling forged treasures to museums. When Jack suddenly dies in a car crash, his wife Adrienne tries to discover what he did on her own. She finds that she knew little about the man she was married to. The more she learns about her husband's possible illegal activities and double life, the more she places her daughter, and herself, in grave danger.

Letting Go stars John Ritter as a widower and Sharon Gless as a lonely unmarried woman. They meet during a group-therapy session. Romance is inevitable, but the road to true happiness is pockmarked by a series of comic complications. Advertised as a straight romantic drama, Letting Go is actually more akin to the screwball comedies of the 1930s, with a strong satirical bent regarding "behavior modification" theories. The made-for-TV film debuted May 11, 1985.

Alan Masters is a despicable businessman with his hands in organized crime. He marries Diane, a kind and gentle woman, and abuses and batters her viciously. Sergeant John Reed has had enough of his city's organized crime and, against the wishes of his dirty-cop superiors, tries to get evidence against Alan Masters. After Alan finds out that Diane has been helping Reed, he beats her to death...and its up to John Reed to put him away for it, and clean up the dirty cops that want to stop him. Part I starts with Diane's death and then, in a flashback, details her struggles against abuse and Reed's struggles as he coaches her to gather evidence against Alan. Part II deals with Reed's struggles with intimidating cops.