Indy's (Bibi) slimy adventure continues as a mysterious slime stone with magical powers suddenly appears from outer space. When the evil Xenia Kobalt takes hold of the stone the entire world bursts into a fight. Indy, the happy alien Klatu and slime friends both new and old have to go to the impossible to stop Xenia.

Something terrible happens: an important slime ingredient is running out, which renders slime making impossible for the whole world! Indy sets out to find the origin of this slimy ingredient. She travels the world with her old and new slime friends and they are faced with a slimy mystery. Can Indy get the slime back?

Dylan is very successful at running his own lunchroom and YouTube channel. Then IJsbrand comes into his life and copies everything he does. Dylan decides to get to the bottom of this and puts fame and friendship at risk.

Indy and Olivia are crazy about making slime, but they run into trouble when a big toy factory boss starts an anti-slime campaign to increase his own toy sales.

Slime creator Indy has to come up with a super cool new slime recipe for a big Slime Gala. When she secretly adds octopus slime while making it, magical colors are created. This is the best slime she's ever made! But when jealous slime creator Benji steals the recipe, everything goes wrong. Can Indy stop Benji and win back her slime fans?

A new teacher in class always takes some getting used to, but Miss Pots beats it all. Kaya and Simon can't get along with her so they decide not to rest until they have gotten rid of Pots...