Dr. Victor Frankenstein neglects the sexual needs of his frigid and frustrated wife Helena. After Helena gets killed in a horse riding accident, Victor decides to bring her back to life. However, Victor's inept assistant Igor accidentally damages Helena's brain and replaces it with a lesbian's brain, so Helena is now a crazed, aggressive, and predatory vixen with a raging insatiable libido.

Self-absorbed and stressed-out yuppie Robert is so caught up with his thankless office job that he neglects his lovely young wife Doris. The sad, unhappy, and frustrated Doris seeks some form of relief and sexual fulfillment from both a lusty lady ghost and two equally voracious female demons.