A holiday craft fair is ground zero for a coven of Satan worshipers who stalk and kidnap a group of locals in their attempt to create a Satanic Nativity with occult spells and grisly slayings.

A mafia drug lord has unleashed a new, highly addictive stimulant on the streets called HT25, derived from sharks held captive in a secret lab, and which causes monstrous side effects. After an explosion and leak at the lab, an army of mutated, bloodthirsty sharks and other creatures are set loose on the world.