From the cage to the big screen, the world's greatest Mixed Martial Arts Champions come together for the first time in a major motion picture. When an MMA world champion is lured into the illegal world of underground cage fighting by an elusive promoter, he quickly realizes that the only way out is to kill or to be killed.

UFC 107: Penn vs. Sanchez was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on December 12, 2009 in Memphis, Tennessee at the FedExForum.

UFC 84: Ill Will was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on May 24, 2008, at the MGM Grand Garden Arena in Las Vegas, Nevada. The card featured the return of Sean Sherk, who was suspended and stripped of his UFC lightweight title after he tested for steroids at UFC 73. He faced B.J. Penn, who had since won the vacated title.

UFC 80: Rapid Fire was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC), that took place on January 19, 2008 at the Metro Radio Arena in Newcastle, England. Sean Sherk was originally slated to fight but tested positive for steroids. With the lightweight championship vacated, the Penn-Stevenson bout was altered to be for the undisputed championship.

UFC 63: Hughes vs. Penn was a mixed martial arts event held by the Ultimate Fighting Championship on September 23, 2006. The event, originally subtitled "Hughes vs. St. Pierre," was scheduled to feature a UFC Welterweight Title match between champion Matt Hughes and Georges St.-Pierre. Nevertheless, a groin injury—which was reported early in August—forced St.-Pierre off the card.

UFC 58: USA vs Canada was a mixed martial arts event held by the Ultimate Fighting Championship on March 4, 2006.Five of the seven Canadian fighters featured, Icho Larenas, Sam Stout, Mark Hominick, Georges St. Pierre, and David Loiseau, were at the time champions in the Canadian TKO Major League MMA promotion. Each fight featured an American fighter against a Canadian fighter.

UFC 112: Invincible was a mixed martial arts event held by the Ultimate Fighting Championship on April 10, 2010, on Yas Island, Abu Dhabi, United Arab Emirates. The main event was for the Middleweight Championship, as Anderson Silva fought Demian Maia.

UFC 94: St-Pierre vs. Penn 2 was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on January 31, 2009. The main event featured the rematch of the UFC Welterweight Champion Georges St-Pierre against the UFC Lightweight Champion BJ Penn for the UFC Welterweight Championship.

UFC 118: Edgar vs. Penn 2 was a mixed martial arts event held by the Ultimate Fighting Championship on August 28, 2010 at the TD Garden in Boston, Massachusetts, United States.

UFC 31: Locked and Loaded was a mixed martial arts event held by the Ultimate Fighting Championship at the Trump Taj Mahal in Atlantic City, New Jersey on May 4, 2001. The event was seen live on pay per view in the United States, and later released on home video.