In the near future, Panther Claw has destroyed the Tokyo Metropolitan Government. The capital government is forced to shift into the provinces. During this time, Honey Kisaragi has transferred to St. Chapel Academy as part of a special course. This special course is the "New Generation Honey" project, where students, including Honey, become Cutie Honey.

Upon rescuing a friend who is being held captive by a wicked classmate and his gang of bullies, 11-year-olds Tetsushi, Yuusuke, and Ryoji unexpectedly find themselves entwined in a supernatural battle against the forces of hell. Armed with courage, wit, and three magical charms given to them by a mysterious hermit, they set out to thwart the evil in a quest, which takes them to the depths of hell and brings them to a final battle with the god of death himself.

A love story full of non-stop action about a man and a woman on the run.