Jesse Struthers and his brother Jake find themselves on the run after a band of men begin murdering their family.

Harvard symbologist Robert Langdon is recruited by the Vatican to investigate the apparent return of the Illuminati – a secret, underground organization – after four cardinals are kidnapped on the night of the papal conclave.

When their drug abusing mother is released from prison determined to rebuild their family, Rey kidnaps his younger brother Oliver and escapes their desert home for the California coast.