Harvey's Last Night on the Avenue concerns a sensitive young man who joins a group of his friends on a bar crawl the night before he moves from New York back to his hometown in Texas. An obsessive and socially awkward person, Harvey ruminates over many of his minor social faux pas that he perceives as huge errors. As the night goes on, he accrues more and more faults in his mind, and becomes increasingly unable to connect with the people around him.

The Sterling sisters and their once close-knit group of friends reunite for a weekend at the family ranch in small town Texas before it's sold. Long simmering conflicts come to a head as they confront the uncertainty of their lives without the connection of home to bind each other.