Manuel and Marian have always been best friends. They are so close that they know each other’s secrets well almost. After all these years, Manuel never had the courage to tell Marian how much he loves her. When Marian’s first love, Lance, returns to the Philippines, she is intent on seeing him again. She brings along Manuel on a chase that brings them around the Philippines and abroad. Manuel now has to decide- Will he let his best friend be happy with her Prince Charming or will he fight for the love that has kept him alive all these years?

Sikil tells the story of two men and a woman who are involved in a bizarre love triangle. These three friends grew up in a small town south of Manila. Enzo is a young closet gay prostitute who's obsessed with his childhood friend who happens to be a call-boy and has a girlfriend. Other interesting characters are the bi-sexual pimp, a regular bathhouse customer, and a sampaguita vendor-pickpocket-shoplifter and caretaker of Adong's daughter.