Inspired by the true story of the women engineers behind India's 2014 Mars Orbiter Mission (MOM), Space MOMs tells the story of normal, middle class working moms who also happen to be rocket scientists working on a very important mission. As the "Space Moms" struggle to pull off an unprecedented feat against impossible odds, they have to balance their brutal work schedules with their family lives.

Revolves around Gautam, a loan collection agent who falls in love with Swecha. After multiple attempts, Gautam succeeds in winning back her love. The plot changes gears as a gang involved in human trafficking kidnap Swecha and the onus is on Gautam to rescue her.