Nanni Moretti recounts in his diary three slice-of-life stories marked by a dry, ironic gaze: in the first, he rides his Vespa through a deserted, sun-drenched summertime Rome; in the second, he visits a reclusive writer friend on an island, who ropes him into an impromptu journey between islets in search of quiet; and in the last, he finds himself grappling with an unknown illness.

Naples, 1959. Pure Mathematics professor Renato Caccioppoli, Bakunin's grandson, is a tortured soul. Recently discharged from the psychiatric hospital, left by his wife, and increasingly disillusioned with academia and the Communist Party, he lives his last days with painful detachment.