Teenager Diane Weaver lives in a small council flat with her brooding father, the groundskeeper of a local church. What no one realises, is how close Diane and her father are.

After the TARDIS collides with a spacecraft delivering human tributes to the evil bull-like Nimon, the Doctor and Romana must stop the fearsome alien's quest to rule the galaxy.

The Doctor returns to Gallifrey, claims his rights and is inaugurated President. It soon turns out that he has led a group of aliens called Vardans to the planet to eradicate them completely. After they are destroyed, the Sontarans take their opportunity and follow them in their invasion until they are destroyed by the Doctor.

The Doctor and Romana arrive on the marsh moon of Delta Magna in search of the next segment of the Key to Time. They are caught in the conflict between the native Swampies and the crew of a chemical refinery. The presence of a gun runner complicates matters; to make things worse, the Swampies intend to awaken Kroll, the giant god that lives beneath the swamps.

Far in the distant future, Earth has become uninhabitable, forcing Mankind to colonise first Mars and then Pluto. No longer the coldest planet in the solar system, Pluto is now warmed by artificial suns. The Doctor, Leela and K9 arrive to discover the exploitation of the Megropolis people by the ruling elite, lead by the Collector. Deep in the Undercity, a small group of revolutionaries plot to overthrow the company and the Doctor is forced to fight the oppression of the people using Fire against Fire...

On the edge of the universe, the Doctor, Leela and K9 encounter a Minyan ship on an epic quest to find their race banks... but their people have encountered the Time Lords before...

The Doctor and Romana learn the second segment of the Key to Time is on the planet Calufrax. Yet they arrive on a planet called Zanak, which has been hollowed out and fitted with hyperspace engines, allowing its insane, half-robot Captain to materialise it around smaller planets and plunder their resources.

The Doctor is summoned by the mysterious and powerful White Guardian, and sent on a quest to find the six segments of the Key to Time, which, once assembled, will restore balance to the Universe. Joining the Doctor and K9 is the smart and sassy Romana, a Time Lord fresh from the Academy. Landing on the wintry planet of Ribos to locate the first segment, the TARDIS crew quickly find themselves embroiled in a little local trouble with a pair of conmen and an unstable warlord...

Searching for the third segment to the Key to Time brings the Doctor and Romana to present-day Earth, where the travellers have to contend with stone circles, Druidic rituals and a not-so-mythical goddess known as the Cailleach.

The final segment of the Key to Time is at the heart of a devastating war between neighbouring planets Atrios and Zeos. The Fourth Doctor discovers that a sinister entity is manipulating events and the cost of obtaining the final segment may be more personal than he imagined.